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Lidocaine may speed up anesthesia recovery in laparoscopic surgery

NCT ID NCT07193836

Symptom relief Sponsor: General Hospital of Ningxia Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether giving lidocaine through a vein can help patients fall asleep faster and wake up sooner after laparoscopic gallbladder or gynecologic surgery. About 150 adults will be split into three groups: one gets a single dose of lidocaine, another gets a continuous infusion, and the third gets a placebo. Researchers will monitor brain activity to see if lidocaine reduces the amount of anesthesia needed and shortens recovery time, aiming to make surgery safer and recovery smoother.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 195 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2025

An estimate. Start dates often move.

Expected to finish

Dec 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 75 years. * ASA physical status I-III. * Scheduled for elective laparoscopic cholecystectomy, laparoscopic * hysterectomy, or laparoscopic ovarian cystectomy. * Expected surgical duration \< 120 minutes. * Preoperative normal cognitive function (MoCA \> 26). * Able and willing to provide written informed consent. Exclusion Criteria: * Known allergy to lidocaine or other amide-type local anesthetics. * History of severe arrhythmias, heart failure (NYHA class III or higher), or epilepsy. * Central nervous system disorders (e.g., stroke, brain trauma, seizure disorders) or psychiatric illness. * Severe hepatic or renal dysfunction (ALT/AST \> 2× ULN, or eGFR \< 60 ml/min/1.73 m²). * Currently taking medications that affect CNS function (e.g., benzodiazepines, antidepressants, antiepileptics). * Pregnant or breastfeeding women. * History of drug or alcohol dependence. * BMI \> 30 kg/m² or \< 18 kg/m². * Inability to understand study procedures or refusal to sign informed consent.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia and procedure related time intervals Cholecystectomy, laparoscopic Gynecologic surgical procedures

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • General Hospital of Ningxia Medical University

    Yinchuan, Ningxia, 750004, China

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