Can a second nerve block double down on Post-Surgery pain relief?
NCT ID NCT07777172
First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time
Summary
This trial tests whether adding a second nerve block to the standard one improves pain control after laparoscopic gallbladder removal. Adults scheduled for this surgery will be randomly assigned to receive either one block or two blocks, both using the local anesthetic bupivacaine. The main goal is to see if the combined approach reduces pain intensity in the first hours after surgery, potentially leading to a more comfortable recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- External oblique intercostal plane block with or without recto-intercostal fascial plane block, using bupivacaine
- What this could lead to
- If the combined blocks work better, it could lead to a simple, drug-free way to ease pain after gallbladder surgery, reducing the need for strong painkillers.
- What could go wrong
- This is a small, early-stage trial, and the added block may not provide extra pain relief. There are also rare risks like bleeding or infection at the injection site.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged between 18 and 75 years * American Society of Anesthesiologists (ASA) physical status I, II, or III * Patients scheduled for elective laparoscopic cholecystectomy Exclusion Criteria: * Known allergy to local anesthetics * Infection at the procedure/injection site * Severe coagulopathy or use of anticoagulants * Chronic opioid consumption or history of neuropathic pain
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ankara Etlik City Hospital
Ankara, Yenimahalle\Ankara, 06170, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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