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Magnetic pulses to the brain may ease depression and sleep troubles
NCT ID NCT07638202
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial investigates whether adding low-intensity transcranial magnetic stimulation (Li-TMS) to standard antidepressant medication can improve depressive symptoms and sleep disorders in people with major depression. The study involves 40 participants who receive either real Li-TMS or a sham procedure, with both groups continuing their usual medication. Researchers also measure inflammation levels and brain-derived neurotrophic factor to explore how the treatment might work.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- low-intensity transcranial magnetic stimulation (Li-TMS)
- What this could lead to
- If it works, this could point toward a non-invasive add-on treatment for depression that also improves sleep and lowers inflammation.
- What could go wrong
- This is a small, early-stage trial with only 40 participants, so results may not apply widely. The treatment is experimental and may not outperform standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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May 2026
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Clinical diagnosis of major depressive disorder * insomnia Exclusion Criteria: * Epilepsy * Alzheimer's Disease
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
1Clinical Epidemiology Research Unit. OOAD Guanajuato. Mexican Social Security Institute, Leon, Mexico,
León, Guanajuato, 37328, Mexico
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Other studies related to the condition(s) this trial covers.
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