Which letrozole schedule boosts ovulation best in PCOS?
NCT ID NCT07448272
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at two ways of taking the drug letrozole to help women with PCOS ovulate and get pregnant. One group takes 5 mg daily for 10 days, the other takes 10 mg daily for 5 days. Researchers will track follicle growth and ovulation to see which schedule is more effective and safe.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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80 people
The number who actually took part.
- Started
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Apr 2025
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 35 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed cases of PCOS women according to Rotterdam criteria. * Age: 18-35 years old. * Primary or secondary infertility Exclusion Criteria: * Women withother causes of anovulation (AsCushing syndrome, late onset congenital adrenal hyperplasia, uncorrected hypothyroidism, uncorrected hyperprolactinemia). * Women with other infertility factors like tubal and uterine causes of infertility, endometriosis, undiagnosed per vaginal bleeding (From history and examination). * History of hypersensitivity to letrozole. * BMI:\< 18.5 kg/m2 and ≥30 kg/m2. * Male factor infertility. * Medical disease (uncontrolled HTN, uncontrolledDM, uncontrolledLiver disease, kidney disease).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Bangladesh Medical University
Dhaka, 1000, Bangladesh
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Other studies related to the condition(s) this trial covers.
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