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New drug combo shows promise for Tough-to-Treat uterine cancer

NCT ID NCT01068249

First seen Nov 18, 2025 · Last updated Jun 15, 2026 · Updated 26 times

Summary

This study tested whether a combination of two drugs, letrozole and everolimus, can help control advanced or recurrent endometrial cancer. 42 participants whose cancer had returned or worsened despite prior treatment were enrolled. The goal was to see if the tumors shrank or stopped growing, while also monitoring safety.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Morristown Memorial Hospital, Women's Cancer Center

    Morristown, New Jersey, 07962, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

endometrium neoplasm Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.