Can a simple blood test predict chemo success in rare cancer?
NCT ID NCT05653388
First seen Jan 04, 2026 · Last updated May 23, 2026 · Updated 22 times
Summary
This study looks at whether a blood test for tumor DNA can help doctors know early if chemotherapy is working for people with advanced leiomyosarcoma, a rare soft tissue cancer. Researchers will collect blood samples before and during treatment, along with tumor tissue and scans, to find markers linked to better outcomes. About 200 participants who are starting their first chemotherapy will take part. The goal is to improve treatment planning, not to test a new therapy.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chris O'Brien Lifehouse
RECRUITINGCamperdown, New South Wales, 2050, Australia
Contact Email: •••••@•••••
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Dana- Farber
RECRUITINGBoston, Massachusetts, 02215, United States
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MD Anderson
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55901, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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Peter MacCallum Cancer Centre
RECRUITINGMelbourne, Victoria, 3000, Australia
Contact Email: •••••@•••••
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Sarcoma Oncology Research Center
RECRUITINGSanta Monica, California, 90403, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Miami
RECRUITINGMiami, Florida, 33136, United States
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University of Michigan Cancer Center
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Contact Phone: •••-•••-••••
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States
Contact Phone: •••-•••-••••
Conditions
Explore the condition pages connected to this study.