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Heart clot registry aims to prevent strokes in thousands

NCT ID NCT06963567

Knowledge-focused Sponsor: Queen Mary University of London Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This study is tracking 1,500 people who either have a blood clot in the heart's main pumping chamber (left ventricular thrombus) or are at high risk for one. Researchers will collect blood samples, scan results, and quality-of-life data over 12 months to learn why clots form and how they respond to treatment. The goal is to improve future care and reduce serious complications like stroke.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better predict and manage left ventricular thrombus, potentially reducing strokes and bleeding complications.
What could go wrong
This is an observational registry, not a treatment trial, so it won't directly test a new therapy. Results may take years and might not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,500 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2024

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with a diagnosis of LV thrombus in the setting of LV dysfunction (acute myocardial infarction, Ischaemic Cardiomyopathy (ICM), dilated cardiomyopathy (DCM)) will be screened. Patients that do not have LV thrombus but are at risk for developing thrombus such as those with severe LV dysfunction, LV aneurysms, large territory infarcts will also be included.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with LV thrombus or; * Patients at risk for developing LV thrombus (e.g severe LV dysfunction, LV aneurysm, MI. Exclusion Criteria: * Age \< 18 years * Unable to consent

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Left ventricular thrombus

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    8 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Basildon University Hospital

    NOT_YET_RECRUITING

    London, Essex, SS16 5NL, United Kingdom

  • Imperial College Healthcare London

    RECRUITING

    London, W12 0HS, United Kingdom

  • James Cook University Hospital

    NOT_YET_RECRUITING

    Middlesbrough, North Yorkshire, TS4 3BW, United Kingdom

  • Lancashire Cardiac Centre

    RECRUITING

    Blackpool, FY3 8NR, United Kingdom

  • Leeds General Infirmary

    RECRUITING

    Leeds, LS1 3EX, United Kingdom

  • Royal Papworth Hospital

    RECRUITING

    Cambridge, Cambridgeshire, CB2 0AY, United Kingdom

  • St Bartholomew's Hospital

    RECRUITING

    London, EC1A 7BE, United Kingdom

  • Sunderland Royal Hospital

    NOT_YET_RECRUITING

    Sunderland, Tyne and Wear, SR4 7TP, United Kingdom

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