New hope for heart attack patients: can a common blood thinner prevent strokes?
NCT ID NCT05892042
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding the blood thinner rivaroxaban (Xarelto) to standard care helps dissolve dangerous blood clots in the heart after a major heart attack. Researchers will track 320 participants to see if the drug reduces strokes and other complications. The goal is to find a better way to manage these clots and improve recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Rivaroxaban (Xarelto)
- What this could lead to
- If successful, this could provide a clearer, safer treatment plan for dissolving dangerous heart clots after a heart attack, reducing stroke risk.
- What could go wrong
- This is a relatively small, early-stage study without a placebo control, so results may not be definitive. Bleeding risk from blood thinners is a known concern.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 320 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2023
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Established ST segment elevation myocardial infarction within 7 days Left ventricular thrombus (LVT) is detected by either cardiac magnetic resonance (CMR) or TTE. Ongoing treatment with dual anti-platelet therapy according to ESC/AHA guidelines at the time of randomization Exclusion Criteria: Clinically or hemodynamically unstable planed major surgeon such as CABG or Valve replacement within next 12 months Concomitant condition that requires anti- coagulation therapy, such as AF, DVT. Any contraindication of anticoagulant therapy History of intracranial hemorrhage; Woman who is currently pregnant, or breastfeeding serious impaired renal and liver functions life expectancy less than 1 year can not provide consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Jilin university
RECRUITINGChangchun, Jilin, 130000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can suctioning clots from heart arteries save more muscle after a heart attack?
- Could an allergy pill mend hearts after an attack?
- Heart clot showdown: could a simpler blood thinner replace warfarin?
- New Clot-Busting drug could change heart attack care
- Could one blood thinner be enough after a heart attack? new trial aims to find out