New radiation method aims to shrink large tumors better
NCT ID NCT07594431
First seen May 23, 2026 · Last updated Jun 20, 2026 · Updated 5 times
Summary
This phase 2 trial compares a new type of radiation called LATTICE radiotherapy with standard palliative radiation for people who have large metastatic tumors (over 2.5 cm). The LATTICE method delivers a very high dose to the center of the tumor while keeping lower doses to the surrounding area. The study will enroll 80 patients and measure how much the tumor shrinks 90 days after treatment. The goal is to see if this approach works better than the standard treatment for controlling tumor growth.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Stanford University
Palo Alto, California, 94304, United States
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LATTICE radiotherapy (a type of radiation that delivers a high dose to the center of the tumor while keeping lower doses to surrounding tissue)
What this could lead to
If it works, this could offer a more effective way to shrink large metastatic tumors, potentially improving symptom control and quality of life.
What could go wrong
This is a small, early-phase trial with only 80 participants, so results may not apply to everyone. The higher radiation dose could also increase side effects like pain or damage to nearby organs.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.