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Laser zaps tooth pain: new study tests precision treatment

NCT ID NCT07287709

Symptom relief Sponsor: Rana Hegaz Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a laser-based procedure to the standard method for treating severe toothache (irreversible pulpitis) in adult molars. Sixty participants will receive either laser or conventional treatment, and healing will be tracked using X-rays and AI analysis. The goal is to see if the laser approach is more effective at relieving pain and preserving the tooth.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Diode laser and sodium hypochlorite solution
What this could lead to
If successful, laser pulpotomy could offer a less painful, more precise alternative to standard root canal treatment for severe toothache.
What could go wrong
This is a small, early-stage trial with only 60 participants. The laser method may not prove more effective than the standard approach, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Permanent molar teeth with symptomatic irreversible pulpitis. * The patient should be ≥ 16 to 50 years old. * Teeth should give positive response to cold testing and clinical diagnosis of SIP with or without periapical rarefaction. * Teeth will be selected only if they are restorable. * Patient medically healthy and free from systemic diseases. ASA I, II. * patients who agreed to participate in the study to attend the control visits. * Teeth with periapical index score (PAI) 1 and 2 will be selected Exclusion Criteria: * Teeth with necrotic pulp, resorption or subgingival caries. * Teeth with open apices. * Medically compromised patients. * Pregnant patients. * Patients with uncontrollable bleeding from the radicular pulp. * Patients with (PAI) score 3-5 will be excluded from the study

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Conditions

The condition(s) this trial relates to.

pulpitis Toothache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Irreversible pulpitis (toothache)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Dentistry

    RECRUITING

    Alexandria, 21527, Egypt

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