Laser vs. phenol: which minimally invasive treatment hurts less?
NCT ID NCT07701772
First seen Jul 14, 2026 · Last updated Sep 02, 2026 · Updated 3 times
Summary
This trial compares two minimally invasive procedures—laser ablation and crystallized phenol application—for treating primary uncomplicated pilonidal sinus disease. Adults with this condition are randomly assigned to one of the two treatments. The main goal is to measure pain on the first day after the procedure, with additional outcomes including wound healing time and recurrence at six months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- laser ablation or crystallized phenol application
- What this could lead to
- If one method proves less painful and faster to heal, it could become the preferred minimally invasive treatment for pilonidal sinus disease.
- What could go wrong
- This is a single-center trial with 120 participants, so results may not apply broadly. Both treatments carry risks of infection or recurrence.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * Diagnosis of primary chronic sacrococcygeal pilonidal sinus disease * Uncomplicated disease * Suitability for minimally invasive treatment * Provision of written informed consent Exclusion Criteria: * Acute pilonidal abscess * History of pilonidal abscess drainage * Previous surgical or interventional treatment for pilonidal sinus disease * Recurrent pilonidal disease * Complex pilonidal disease or marked lateral extension * Immunosuppression, chronic steroid use, or systemic conditions that may significantly impair wound healing * Inability to attend regular follow-up * Refusal to participate in the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sanliurfa Education and Research Hospital
RECRUITINGSanliurfa, Şanlıurfa, Turkey (Türkiye)
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