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Laser and vitamin d may shorten time in braces

NCT ID NCT07286474

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding low-level laser therapy and vitamin D3 supplements to standard braces can help move teeth faster and reduce pain. Fifty adults with crowded lower front teeth will be split into groups: braces alone, braces plus vitamin D, or braces plus both laser and vitamin D. Researchers will measure tooth movement, pain, and root health over several months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
low-level laser therapy and vitamin D3 supplements
What this could lead to
If it works, this could make orthodontic treatment faster, less painful, and require fewer dental visits.
What could go wrong
This is a small, early-stage trial with only 50 participants, so results may not apply to everyone. The combination may not work better than braces alone, and there is a risk of root resorption or pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Participants requiring orthodontic treatment for crowding in the range of 4 to 8 mm in the lower anterior segment. • Age range: 18 to 40 years. • Angles Class I, II or III malocclusion • Fully erupted permanent dentition • Good oral and general health \- Normal range of Vitamin D levels Exclusion Criteria: * Deficiency of Vitamin D levels below normal range. • Medically compromised patients with thyroid, parathyroid, or renal and liver diseases. Patients on medication, especially corticosteroid and anticonvulsant drugs • Poor oral hygiene • Pregnancy • Lactation • History of craniofacial abnormalities or syndromes that may affect orthodontic tooth movements. • Participants failing to complete the Vitamin D supplementation log sheets will be excluded to ensure accurate data collection. • Inability to comply with the study protocol or unable to complete the study due to personal, medical, or logistical reasons (e.g., missed follow-up visits or failure to undergo assessments) will be excluded to maintain data integrity and minimize biases from incomplete participation.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Armed Forces Hospital

    Madinah, Madinah, 42314, Saudi Arabia

More trials for these conditions

Other studies related to the condition(s) this trial covers.