Coated braces wires put to the test: can a nanocoating speed up tooth straightening?
NCT ID NCT07813117
First seen Sep 10, 2026 · Last updated Sep 11, 2026 · Updated 1 time
Summary
Researchers at Al-Azhar University are testing whether orthodontic archwires coated with zirconium dioxide nanoparticles move crowded teeth faster than standard uncoated wires. The trial enrolls 20 teenagers, ages 13 to 19, who have moderate crowding of the upper front teeth and no prior braces. During the leveling and alignment phase of treatment, each participant receives either a coated or uncoated nickel-titanium wire, and researchers track how quickly the teeth straighten using a standard crowding index. The study also looks at patient comfort and clinical outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- zirconium dioxide nano-coated nickel-titanium orthodontic archwire
- What this could lead to
- If the coating helps teeth move faster, orthodontists could shorten the leveling and alignment stage of braces for teenagers with crowded front teeth.
- What could go wrong
- This is a small study of 20 teenagers with moderate crowding, so any difference in tooth movement may be too small to matter or may not apply to other patients. Coated wires can also wear or flake, and the trial does not report long-term safety data.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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13 to 19 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants within the age range of 13 to 19 years. * Moderate crowding (4-6 mm) in the maxillary anterior segment, evaluated using the Little Irregularity Index (LII), indicating the need for treatment with a fixed appliance without extractions. * Patients in permanent dentition with all teeth had fully erupted ( excluding 3rd molars) * Good oral hygiene. * No previous orthodontic treatment. Exclusion Criteria: * Transverse and/or vertical skeletal dysplasia or craniofacial malformation * Retained primary or missing permanent teeth in the maxillary anterior area. * Present or history of periodontal diseases. * Physical or mental disability. * Systemic diseases or regular use of medications that could interfere with orthodontic tooth movement.
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Conditions
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