Laser and peroxide combo shows promise for implant gum disease
NCT ID NCT07287956
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a special light-activated treatment, called oxygen high-level laser therapy, could improve gum health around dental implants. Sixteen adults with gum infections around their implants received either laser therapy with hydrogen peroxide or laser alone after standard cleaning. Researchers measured gum pocket depth, bleeding, and bacteria levels to see which treatment worked better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- oxygen high-level laser therapy (diode laser and hydrogen peroxide)
- What this could lead to
- If it works, this could offer a better way to treat gum infections around dental implants without surgery.
- What could go wrong
- This was a very small study with only 16 participants, so results may not apply to everyone. The treatment is still experimental and not yet proven better than standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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16 people
The number who actually took part.
- Started
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Feb 2024
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients 18 years or older. * Patients diagnosed with peri-implant disease (peri-implant mucositis or peri-implantitis) according to the 2017 World Workshop criteria in at least two non-adjacent, single-crown, bone-level dental implants. * Patients that have not undergone periodontal treatment and/or were prescribed antibiotics in the last three months prior to initial visit. * Patients with a healthy periodontal status * At least 1 year of functional implants. * Non-Smokers. Exclusion Criteria: * Immunocompromised patients. * Pregnancy or breastfeeding. * Known allergies to any materials used in the study. * Patients classified as ASA Physical Status ≥ III.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Jordan University of Science and Technology
Irbid, Alabama, 22110, Jordan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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