Can a drug combo heal breathing tube damage to the voice box?
NCT ID NCT03250975
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 30 times
Summary
This study tracks how often people get voice box injuries after having a breathing tube for 1 to 7 days in the ICU. It also tests whether a 14-day course of budesonide and azithromycin can help heal those injuries and improve breathing. About 64 adults who had a breathing tube will take part.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
budesonide and azithromycin
What this could lead to
If it works, this could point toward a treatment to speed healing of voice box injuries from breathing tubes.
What could go wrong
This is a small, early-phase study with only 64 participants, so results may not apply widely. The drugs may not improve symptoms.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.