Nerve block showdown: which procedure eases pelvic pain best?
NCT ID NCT06719635
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two minimally invasive procedures to treat chronic pelvic pain: laparoscopic presacral neurectomy and fluoroscopically guided nerve block. Sixty-two adults with pelvic cancer-related pain who still have significant pain despite standard treatment will be randomly assigned to one of the two procedures. The main goal is to see which method provides better pain relief and reduces the need for painkillers over six months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block procedure
- What this could lead to
- If successful, this could offer a more effective, lasting option for managing chronic pelvic pain and reducing daily painkiller use.
- What could go wrong
- This is a small, early-stage trial with only 62 participants. Results may not apply to all patients, and both procedures carry risks like bleeding or nerve damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
62 people
The number who actually took part.
- Started
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Dec 2024
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient acceptance. * Body mass index \< 35 kg/m2. * Adult patients with chronic pelvic and perineal pain due to pelvic cancer. * Visual Analog Scale pain score ≥ 5 on a 0-10 scale despite treatment with a standard analgesic. Exclusion Criteria: * Uncooperative patient. * Patients with coagulopathy, infection at the site of injection, severe cardiac compromise, or intolerance to sympathetic block.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Zagazig university hospital
Zagazig, Al-Sharkia, 44519, Egypt
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