New combo therapy aims to boost radioactive iodine's power against stubborn thyroid cancer
NCT ID NCT05783323
First seen Nov 16, 2025 · Last updated May 22, 2026 · Updated 27 times
Summary
This study tests whether the drug larotrectinib can make thyroid cancer cells more sensitive to radioactive iodine therapy. It includes children and adults with a specific genetic change (NTRK fusion) whose cancer has spread to the lungs. The goal is to see if this combination can shrink or eliminate lung tumors better than radioactive iodine alone.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
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Locations
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Seattle Children's Hospital
RECRUITINGSeattle, Washington, 98105, United States
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St. Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 19807, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94115, United States
Contact Email: •••••@•••••
Conditions
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