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New vaccine combo takes on Hard-to-Treat cancers

NCT ID NCT06411691

First seen Nov 20, 2025 · Last updated May 19, 2026 · Updated 23 times

Summary

This early-phase study tests a combination of a vaccine targeting mutant KRAS proteins and two immunotherapy drugs (balstilimab and botensilimab) in adults with advanced colorectal or pancreatic cancer that has not responded to first-line chemotherapy. The goal is to see if the treatment can shrink tumors or slow disease progression. About 54 participants will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sidney Kimmel Comprehensive Cancer Center

    RECRUITING

    Baltimore, Maryland, 21231, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.