New surgery may keep Crohn's disease at bay after bowel resection
NCT ID NCT03256240
First seen Jan 11, 2026 · Last updated Jun 20, 2026 · Updated 21 times
Summary
This study tests whether a newer surgical method called Kono-S anastomosis can better prevent Crohn's disease from returning after bowel surgery compared to the standard side-to-side technique. About 600 adults with Crohn's disease needing bowel resection will be randomly assigned to one of the two procedures. The main goal is to see if the Kono-S method leads to fewer signs of disease recurrence within 6 months and over the long term.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Azienda Ospedaliero-Universitaria Careggi
RECRUITINGFlorence, Florence, 50134, Italy
Contact Email: •••••@•••••
Contact
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Baylor College of Medicine
TERMINATEDHouston, Texas, 77030, United States
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Baylor Scott & White Research Institute
TERMINATEDDallas, Texas, 75204, United States
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Charité Campus Benjamin Franklin
RECRUITINGBerlin, 12203, Germany
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Helsinki University Hospital
TERMINATEDHelsinki, Helsinki, 00029, Finland
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Hospital Universitario Vall d'Hebron
TERMINATEDBarcelona, Barcelona, 08035, Spain
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Humanitas University Hospital
RECRUITINGRozzano, Milan, 20089, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital
TERMINATEDBoston, Massachusetts, 02114, United States
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Policlinico University Hospital
RECRUITINGNaples, Italy
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Theresien Hospital and St. Hedwigs Clinic gGmbH
RECRUITINGMannheim, 68165, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University Clinics Gasthuisberg Herestraat
RECRUITINGLeuven, 3000, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Oklahoma
TERMINATEDOklahoma City, Oklahoma, 73112, United States
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University of Washington Medical Center
TERMINATEDSeattle, Washington, 98195, United States
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Universitätsklinik Würzburg
RECRUITINGWürzburg, Wurzburg, D-97080, Germany
Contact Email: •••••@•••••
Contact
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Weill Cornell Medical College
RECRUITINGNew York, New York, 10065, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
surgical procedure (Kono-S anastomosis)
What this could lead to
If successful, this could offer a better surgical option to reduce the chance of Crohn's disease coming back after surgery.
What could go wrong
This is a surgical technique comparison, not a new drug. Results may vary, and long-term benefits are still uncertain until the trial completes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.