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New nerve block could ease pain after knee surgery

NCT ID NCT06920186

First seen Jan 05, 2026 · Last updated Jun 23, 2026 · Updated 17 times

Summary

This study tests whether a newer nerve block (quadri-block) provides better pain relief and recovery after total knee replacement compared to the standard method (adductor canal block plus surgical infiltration). About 100 adults with knee arthritis scheduled for knee replacement will be randomly assigned to one of the two procedures. The main goal is to see which approach leads to a better recovery 24 hours after surgery, measured by a quality-of-recovery questionnaire.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Clinique des Côtes du Rhône

    NOT_YET_RECRUITING

    Roussillon, 38150, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Privé Claude Galien

    RECRUITING

    Quincy-sous-Sénart, 91480, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nerve block procedure (quadri-block or adductor canal block plus surgical infiltration)

What this could lead to

If successful, this could point to a better pain management technique for knee replacement surgery, leading to faster and more comfortable recovery.

What could go wrong

This is a small, early-stage trial with only 100 participants, so results may not apply to everyone. The new block may not prove better than the standard approach.

Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.