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Knee replacement showdown: vitamin e vs. standard plastic

NCT ID NCT04618016

First seen Feb 28, 2026 · Last updated May 24, 2026 · Updated 10 times

Summary

This study compares two types of plastic used in total knee replacements: one with vitamin E and one without. About 605 adults with knee arthritis or similar conditions will be followed for years to see which material lasts longer and leads to better knee function. The goal is to improve the durability and performance of knee implants.

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Contacts and locations

Locations

  • Brüderhaus Koblenz

    Koblenz, Rhineland-Palatinate, 56073, Germany

  • CHU Amiens-Picardie

    Amiens, 80054, France

  • Hôpital Sud - CHU de Grenoble

    Échirolles, Isere, 38130, France

  • Krankenhaus Reinbek, St. Adolf Stift

    Reinbek, 21465, Germany

  • Lukas Krankenhaus

    Bünde, North Rhine-Westphalia, 32257, Germany

  • Park-Klinik Weißensee

    Berlin, 13086, Germany

  • Universitätsklinikum Rostock, Klinik für Orthopädie

    Rostock, 18057, Germany

  • Waldkliniken Eisenberg

    Eisenberg, 07607, Germany

Conditions

Explore the condition pages connected to this study.