Knee replacement showdown: does vitamin e make plastic last longer?

NCT ID NCT04618016

First seen Feb 28, 2026 · Last updated May 16, 2026 · Updated 9 times

Summary

This study looks at 605 people getting knee replacements to compare two types of plastic used in the artificial joint: one with vitamin E and one without. The goal is to see which plastic wears down less and helps patients move better over many years. Participants must be between 18 and 80 years old and willing to attend long-term checkups.

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Contacts and locations

Locations

  • Brüderhaus Koblenz

    Koblenz, Rhineland-Palatinate, 56073, Germany

  • CHU Amiens-Picardie

    Amiens, 80054, France

  • Hôpital Sud - CHU de Grenoble

    Échirolles, Isere, 38130, France

  • Krankenhaus Reinbek, St. Adolf Stift

    Reinbek, 21465, Germany

  • Lukas Krankenhaus

    Bünde, North Rhine-Westphalia, 32257, Germany

  • Park-Klinik Weißensee

    Berlin, 13086, Germany

  • Universitätsklinikum Rostock, Klinik für Orthopädie

    Rostock, 18057, Germany

  • Waldkliniken Eisenberg

    Eisenberg, 07607, Germany

Conditions

Explore the condition pages connected to this study.