New study aims to ease pain after knee surgery without extra opioids
NCT ID NCT07577869
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two different nerve blocks to see which one works better for pain control after total knee replacement. Sixty adults having knee surgery will be randomly assigned to receive one of the blocks along with standard pain medicines. The goal is to reduce the need for strong painkillers like morphine and help people recover more comfortably.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18 and older * ASA I-III * Patients scheduled for elective unilateral knee replacement * Eligibility for and consent to spinal anesthesia Exclusion Criteria: * History of allergy or anaphylaxis to local anesthetics, animal gelatin, or chlorhexidine * Bleeding diathesis/inability to discontinue anticoagulants * Infection (at the injection site/sepsis) * Neurological disorders or cognitive impairment affecting pain perception * Pregnancy, breastfeeding * Patients under 18 years of age
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Kayseri City Hospital
RECRUITINGKayseri, Kocasinan, 38080, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- What do knee replacement patients really need to know? a study asks them
- Prepping the knee before surgery: a new approach to better recovery
- Which nerve drug wins the battle against Post-Surgical knee pain?
- Can a single steroid dose transform knee replacement recovery?
- Can the right anesthesia get knee replacement patients moving faster?
- Can relaxation exercises boost recovery after knee replacement?