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New combo therapy shows promise for stiff knees

NCT ID NCT06954363

Symptom relief Sponsor: Khyber Medical University Peshawar Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding two specific hands-on therapies—muscle energy techniques and Mulligan mobilization—to standard physical therapy could improve hamstring flexibility and reduce daily limitations in people with knee osteoarthritis. Twenty-four adults aged 40 and older with mild to moderate knee arthritis took part. The goal was to see if these extra treatments help patients move better and feel less pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

24 people

The number who actually took part.

Started

Apr 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed cases of osteoarthritis (Grade 1 to 3) * X-ray showing Grades I to III on Kellgren Lawrence scale of Osteoarthritis. * Residents of Peshawar verified via NADRA CNIC * Both genders will be included with unilateral or bilateral knee involvement. * Age group 40 and above. * Duration of Knee pain for more than 3 months. Exclusion Criteria: * History of any previously known neurological conditions i.e. stroke, peripheral neuropathy * Fractures in treatment limb. * Suspicious of malignancy around the knee joint. * Recent under gone surgery * Recent Intra-articular injection. * Significant comorbid diseases and disabilities are excluded from the study

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis

Contacts and locations

Locations

  • Alkhidmat Hospital Peshawar

    Peshawar, KPK, Pakistan

  • Bibi Zahida Memorial Hospital, NCS University System

    Peshawar, KPK, Pakistan

  • Hayatabad Medical Complex Peshawar

    Peshawar, KPK, 25000, Pakistan

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