Which shot works best for aching knees? new study to find out
NCT ID NCT07243392
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study will compare three common injection treatments for knee osteoarthritis: steroids, dextrose prolotherapy, and platelet-rich plasma (PRP). Seventy-two adults aged 40 to 80 with moderate to severe knee arthritis will receive one of the three injections. Researchers will measure pain and function over time to see which option provides the best and longest-lasting relief.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Health Sciences
Lahore, Punjab Province, 64200, Pakistan
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Steroid injection, dextrose prolotherapy, or platelet-rich plasma (PRP) injection
What this could lead to
If successful, this study could show which injection works best for long-term knee pain relief and function in osteoarthritis, helping guide treatment choices.
What could go wrong
This is a small, early-stage comparative study with no blinding, so results may be biased. It is not yet recruiting, and individual responses to injections vary widely.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.