Can Brain-Zapping gadgets ease knee pain better than standard TENS?
NCT ID NCT07258693
First seen Jan 03, 2026 · Last updated Jun 19, 2026 · Updated 25 times
Summary
This study tests whether adding a noninvasive nerve stimulation device (NESA) to exercise is better than adding standard TENS for knee osteoarthritis. Researchers will measure pain, stiffness, mobility, mental health, and quality of life in 110 people over 60. Both groups will do the same exercise program for 8 weeks, but one group gets NESA and the other gets TENS.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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ICOT rehabilitation centers
Las Palmas de Gran Canaria, Spain
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
therapeutic exercise combined with noninvasive neuromodulation (NESA) or transcutaneous electrical nerve stimulation (TENS)
What this could lead to
If successful, this could point toward a more effective way to reduce pain and improve mobility and mental health in older adults with knee osteoarthritis.
What could go wrong
This is a small, early-stage study with no blinding, so results may not be definitive. The benefits seen might not apply to all patients or last long-term.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.