OSTEO ARTHRITIS KNEE

This study tests whether a surgical robot (ROSA Knee) can help surgeons make last-minute adjustments to knee replacement plans based on the condition of the patient's soft tissues during the operation. About 80 adults with knee arthritis will be enrolled and followed for 2 years …

This study compares two types of knee replacement surgery for people with severe arthritis on the inner side of the knee. One group gets a standard total knee replacement, the other gets a robotic-assisted partial knee replacement. The goal is to see which approach leads to bette…

This study tests whether a special putty placed in the bone gap during knee realignment surgery can reduce pain right after the operation. About 40 adults with knee osteoarthritis will be randomly assigned to get the putty or standard surgery. The goal is to see if the putty help…

This study tests whether adding metformin, a diabetes drug, to usual care can reduce pain and improve knee function in people with knee osteoarthritis. About 70 adults aged 30 to 60 with moderate knee arthritis will take metformin or a placebo alongside their regular treatments. …

This study is testing a device called the MISHA Knee System to see if it safely reduces pain and improves function in people with knee osteoarthritis. About 120 adults aged 25 to 65 with moderate to severe knee pain that hasn't improved with other treatments will receive the impl…

This study tests whether adding a therapy that involves breathing air with low and high oxygen levels (intermittent hypoxia-hyperoxia) to standard physical therapy can reduce pain and improve daily function in people with knee osteoarthritis. The trial will include 60 adults aged…

This study tests a new treatment called OA-SYS for people with moderate to severe knee osteoarthritis. The main goal is to see if it is safe and well-tolerated. Researchers will also check if it reduces pain and improves knee function. About 400 adults aged 35 to 75 will take par…

This study compares a new gel-like substance (Arthrosamid®) injected into the knee joint against the standard steroid injection for treating knee osteoarthritis. The goal is to see which one better reduces pain, stiffness, and improves daily function. About 200 adults with modera…