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Which angle builds stronger knees? small study tests two positions

NCT ID NCT07456254

Symptom relief Sponsor: Indonesia University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether changing the angle of a leg exercise machine (N-K Table) from 0° to 50° helps people with knee osteoarthritis activate their thigh muscles more. Forty-three women aged 50-65 with knee osteoarthritis did isotonic knee extensions at both angles. Muscle activity was measured using surface electromyography. The goal is to find the best angle for strengthening exercises.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Isotonic quadriceps exercise using N-K Table at different load angles
What this could lead to
If successful, this could help physical therapists choose the best exercise angle to strengthen thigh muscles in people with knee osteoarthritis.
What could go wrong
This is a small, completed study with only 43 participants, so results may not apply to everyone. It measures muscle activation, not long-term pain or function improvement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

43 people

The number who actually took part.

Started

Jan 2024

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 65 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed with unilateral or bilateral knee osteoarthritis (OA), grade 2 or 3, in the subacute or chronic phase based on the criteria of the American College of Rheumatology (ACR) and Kellgren-Lawrence classification. * Female, aged 50-65 years, based on ACR diagnostic criteria. * Knee flexion-extension range of motion of at least 0-120 degrees. * Normal cognitive function as assessed using the Montreal Cognitive Assessment Indonesia Version (MoCA-INA) (score ≥26-30) Exclusion Criteria: * Knee joint instability due to ligament laxity in the cruciate or collateral ligaments obtained from physical examination (valgus/varus test and anterior/posterior drawer test) or previous supporting examination. * Presence of deformity in the form of genu varus, genu valgus, or genu recurvatum (Q angle 12-20°). * History of knee injury (fracture, ligament rupture, or meniscus) or having undergone knee surgery. * Pain or instability of the ankle joint obtained from physical examination. * Stroke or disorders of the central and peripheral nervous system. * Patients with metabolic diseases such as diabetes mellitus and heart disease or other autoimmune diseases based on medical records in unstable condition with pre-prandial capillary blood glucose ≠ 80-130 mg/dL or 1-2 hours post-prandial capillary blood glucose ≠ \<180 mg/dL, systolic blood pressure ≠ 90-140 mmHg and diastolic blood pressure ≠ 60-90 mmHg. * Pain durin loaded knee extension exercise greatetr than 3 on the Visual Analogue Scale (VAS)

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis Osteearthritis

Contacts and locations

Locations

  • Department of Physical Medicine and Rehabilitation, Dr. Cipto Mangunkusumo General Hospital

    Jakarta, DKI Jakarta, 10430, Indonesia

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