New study aims to stop knee implants from failing in obese women
NCT ID NCT06019832
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at 54 obese women getting knee replacements to see if a stemmed or non-stemmed tibial implant works better. The goal is to find out which type reduces the risk of the implant collapsing or loosening over time. Researchers will track these outcomes to guide future surgical choices.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help surgeons choose better implant designs for obese patients, potentially reducing the need for repeat knee surgeries.
- What could go wrong
- This is a small, observational study with only 54 participants, so results may not apply to all patients. It does not test a new treatment, only compares existing implant types.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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54 people
The number who actually took part.
- Started
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Aug 2023
- Expected to finish
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Dec 2032
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 99 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * Female adult patients with severe osteoarthritis scheduled to have primary total knee arthroplasty * Age 40 or older * 35 kg/m2 and above * Only patients from the PI's clinic will be included. * Women who are still menstruating and are currently on contraceptives and women who are in menopause. Exclusion Criteria: * Patients who have some active local or widespread infection (including secondary or inflammatory osteoarthritis) * medical conditions that put them at risk of complications or death during and after the study would not be eligible for surgery * Patients with previous knee surgery on arthroplasty site will be excluded * Pregnant patients and women who are capable of getting pregnant
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Iowa Health Care Medical Center North Liberty
North Liberty, Iowa, 52317, United States
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