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New study aims to cut unnecessary antibiotics in ICU patients

NCT ID NCT07211620

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 32 times

Summary

This study tests whether using changes in procalcitonin levels over time (kinetics) is better than using a single procalcitonin value to decide when to start antibiotics in critically ill patients with suspected infection. About 250 adults in the ICU will be randomly assigned to one of two antibiotic-starting protocols. The goal is to reduce unnecessary antibiotic use while ensuring patient safety.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Saint Margaret's Hospital

    NOT_YET_RECRUITING

    Budapest, 1032, Hungary

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Semmelweis University, Department of Intensive Therapy

    RECRUITING

    Budapest, 1082, Hungary

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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