Tiny study tests supplement to wake up 'dead' kidneys
NCT ID NCT07555327
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study tested an oral supplement made from generally recognized as safe (GRAS) ingredients in 8 people with end-stage kidney disease. Two participants had not produced urine for 16 and 22 years. The goal was to see if the supplement could restore even a small amount of urine output and improve kidney markers. Because the study is very small and observational, the results are not conclusive.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- oral nutritional supplement (GRAS ingredients)
- What this could lead to
- If it works, this could point toward a way to restore some kidney function in patients with end-stage renal disease, potentially reducing dialysis dependence.
- What could go wrong
- This is a very small, early observational study with only 8 participants. The results may not apply to others, and the supplement is not a proven treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
8 people
The number who actually took part.
- Started
-
Feb 2026
- Finished
-
May 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of a specific cohort of 8 adult patients (diabetic and non-diabetic) diagnosed with Stage 5 Chronic Kidney Disease (CKD). The group is characterized by a wide spectrum of renal impairment, ranging from patients with residual urine output to individuals in total renal arrest on long-term hemodialysis. A key feature of this population is the inclusion of patients with extreme periods of anuria, specifically documenting cases of 16 years and 22 years of total renal inactivity prior to the observation period
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
-
Male participants only
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Sampling Method: Non-Probability Sample Criteria: Patients with confirmed Stage 5 CKD on or off dialysis, with documented periods of renal inactivity ranging from residual function to 20+ years of total arrest.ion Criteria: * Aged 18 and older" et "Diagnosed with ESRD (End-Stage Renal Disease)". Exclusion Criteria: * Pregnant women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Amar hocine Zireg
Bordj Bou Arreridj, Wilaya de Bordj Bou Arréridj, 34000, Algeria
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