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Ketone drink study reveals muscle secrets in aging men

NCT ID NCT05732909

Knowledge-focused Sponsor: University of Aarhus Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a ketone drink improves muscle function in 25 healthy men (12 young, 12 older). Participants drank a ketone monoester and underwent MRI scans, tracer infusions, and bike/dynamometer tests. Researchers compared results within and between age groups to see if age changes the effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

25 people

The number who actually took part.

Started

Dec 2022

Finished

Jan 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 85 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male 20-25 years old (n = 12) OR male 65-85 years old (n = 12) * BMI range: 19 to 27 * Stable weight (\< 5% change over last 6 months) * Less than 3 x 60 min of structured exercise per week. Exclusion Criteria: * Medication that affect energy metabolism. * Non-MR-compatible metals or electric devices in the body. * Anaemia or bleeding disorders. * Heart, lung or other disease that affects the subjects ability to exercise. * Smoking. * Drug abuse. * Lack of compliance. * Known allergy towards local anaesthetics. * Any condition that the principal investigator considers unsuitable for the subject's ability to complete the study.

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Conditions

The condition(s) this trial relates to.

Ketosis metabolic disease muscle tissue disorder skeletal muscle disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Ketonemia Metabolism disorder Muscle disorder

Contacts and locations

Locations

  • Steno Diabetes Center Aarhus

    Aarhus, Aarhus N, 8200, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.