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Could a High-Fat, Low-Carb diet help men breathe easier with COPD?

NCT ID NCT07664111

Disease control Sponsor: Agri Ibrahim Cecen University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This pilot study investigates whether an 8-week ketogenic diet—high in fat and very low in carbs—can improve lung function, reduce inflammation, and boost exercise capacity in men aged 40–75 with mild-to-moderate COPD. Participants are randomly assigned to either the ketogenic diet or standard dietary advice. The study aims to see if this dietary approach is feasible and offers any benefits for managing COPD.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ketogenic diet
What this could lead to
If effective, this diet could become a complementary approach to help manage COPD symptoms and improve quality of life.
What could go wrong
This is a small pilot study with only 34 men, so results may not apply to everyone. The diet is restrictive and may be hard to follow long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

34 people

The number who actually took part.

Started

Jan 2026

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 75 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male sex * Age between 40 and 75 years * Clinically stable chronic obstructive pulmonary disease (COPD) * GOLD stage I or II COPD * No acute COPD exacerbation within the previous 3 months * Stable pharmacological treatment for at least 4 weeks before enrollment * Ability to complete study assessments and comply with dietary instructions * Provision of written informed consent Exclusion Criteria: * GOLD stage III or IV COPD * Uncontrolled cardiovascular disease * Chronic kidney disease * Severe hepatic dysfunction * Active malignancy * Insulin-dependent diabetes mellitus * Participation in another dietary intervention program within the previous 3 months * Inability to complete study assessments * Contraindications to dietary carbohydrate restriction * Refusal or inability to provide informed consent

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic obstructive pulmonary disease (COPD)

Contacts and locations

Locations

  • Ağrı İbrahim Çeçen University

    Ağrı, Turkey (Türkiye)

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