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Ketamine after surgery may ward off depression in At-Risk patients

NCT ID NCT05233566

First seen Feb 13, 2026 · Last updated May 21, 2026 · Updated 9 times

Summary

This study tested whether giving a low-dose ketamine drip after surgery could prevent depressive symptoms in 32 neurosurgical patients who had a history of depression. Researchers measured depression scores before surgery and for two weeks after. The main goal was to see if a larger trial is possible, not to prove the treatment works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.