Ketamine after surgery may ward off depression in At-Risk patients

NCT ID NCT05233566

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether giving a low-dose ketamine drip after surgery could prevent depressive symptoms in 32 neurosurgical patients who had a history of depression. Researchers measured depression scores before surgery and for two weeks after. The main goal was to see if a larger trial is possible, not to prove the treatment works.

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Conditions

The condition(s) this trial relates to.

depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States