850 knee patients tracked to uncover why MPFL surgery sometimes fails
NCT ID NCT06883396
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 850 people aged 10–35 who are having surgery for a kneecap that keeps dislocating. Researchers want to find out what factors increase the risk of the kneecap dislocating again after surgery. Participants will fill out surveys about their knee function and activity level one and two years after the operation.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 850 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2023
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients presenting to the participating surgeons for treatment of recurrent patellar instability
- Ages
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10 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 10-35 years old * Recurrent patellar instability with at least one episode defined as either (1) a dislocated patella requiring reduction in the emergency department or (2) a convincing history for dislocation, associated with full giving way, and the following physical findings: (a) hemarthrosis or effusion, (b) tenderness along the medial retinaculum, and (c) apprehension when laterally directed force was applied to the patella or (3) MRI-documented dislocation with associated bone bruises Exclusion Criteria: * Previous ipsilateral knee surgery * Obligatory/fixed/habitual patella dislocation or subluxation * Unloadable inferior or lateral chondral damage on the patella that would require a tibial tubercle transfer for unloading purposes * Pathologic tibiofemoral instability
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
16 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Boston Children's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229, United States
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Cleveland Clinic
NOT_YET_RECRUITINGCleveland, Ohio, 44195, United States
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Duke Health
RECRUITINGWake Forest, North Carolina, 27587, United States
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Hospital for Special Surgery
RECRUITINGNew York, New York, 10021, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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Mayo Clinic
NOT_YET_RECRUITINGRochester, Minnesota, 55905, United States
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Midwest Orthopaedics at Rush
RECRUITINGChicago, Illinois, 60612, United States
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Mount Sinai
NOT_YET_RECRUITINGNew York, New York, 10012, United States
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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Ohio State University Wexler Medical Center
RECRUITINGDublin, Ohio, 43016, United States
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Oregon Health & Science University
RECRUITINGPortland, Oregon, 97239, United States
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Scottish Rite for Children
RECRUITINGDallas, Texas, 75219, United States
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Stanford University
RECRUITINGRedwood City, California, 94063, United States
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University of Florida
RECRUITINGGainesville, Florida, 32607, United States
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University of Iowa
RECRUITINGIowa City, Iowa, 52242, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A new physical therapy twist could rebuild knees after dislocation
- Which tape wins for knee pain? new study pits kinesio vs McConnell
- Finger-Guided knee surgery offers less trauma for patellar pain
- Kneecap study: does surgery keep young athletes stable?
- Knee pain study tests which therapy works best
- Knee surgery success may depend on bone alignment, study finds