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Ultrasound-Guided head tilt could optimize brain pressure in ICU

NCT ID NCT07665606

Knowledge-focused Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will test whether using ultrasound to guide how a patient's head is tilted can improve blood flow to the brain. Researchers will measure brain pressure and blood flow in 30 ICU patients as they are moved from lying flat to a 30-degree angle. The goal is to find a personalized tilt angle that maximizes brain perfusion without blocking blood drainage from the head.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple, non-invasive method to personalize head positioning for brain-injured patients, potentially improving blood flow and reducing complications.
What could go wrong
This is a very early, small study (30 participants) that only measures short-term effects. The approach may not work for all patients or may not translate to better long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patient hospitalized in the neurocritical care unit or the trauma unit

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients ≥ 18 years old * Hospitalized in the neurocritical care unit or the trauma unit * Scheduled for nursing care requiring a supine position. * Arterial catheter allowing continuous measurement of mean arterial pressure. * Central venous catheter for continuous measurement of central venous pressure. * External ventricular drain or intracranial pressure sensor for intracranial pressure monitoring. * Bed with controlled inclination capability. * Clinically stable condition allowing transient positional changes (as judged by the clinician). * Not included, or planned to be included in another trial. Exclusion Criteria: * Contraindication to trunk mobilization. * Being a minor or placed under supervision. * Hemodynamic or respiratory instability. * Uncontrolled intracranial hypertension, refractory arterial hypertension, or severe dysautonomia. * Pregnancy or breastfeeding. * Refusal to participate in the study.

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Conditions

The condition(s) this trial relates to.

intracranial hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Critical care Intracranial pressure

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bordeaux university hospital

    Bordeaux, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.