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New filler takes on juvederm in battle of the smile-line fixers

NCT ID NCT07265791

First seen Dec 08, 2025 · Last updated May 24, 2026 · Updated 23 times

Summary

This study compares a new injectable filler called JTM104 to the well-known Juvederm for temporarily improving moderate to deep smile lines (nasolabial folds). About 100 adults aged 19 to 75 with matching wrinkles on both sides of the nose will receive one filler on each side to see if JTM104 works as well. The goal is to check safety and how well each filler smooths wrinkles.

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