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New hope for advanced gut cancers: experimental drug enters human trials

NCT ID NCT06663319

First seen Oct 01, 2025 · Last updated May 20, 2026 · Updated 32 times

Summary

This early-phase study tests an experimental drug called JNJ-89402638 in people with advanced colorectal or stomach cancer that has spread and not responded to prior treatments. The study aims to find the safest dose and check if combining the drug with standard therapies like bevacizumab or chemotherapy is tolerable. About 220 participants will be enrolled to monitor side effects and drug levels in the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

  • Community Health Network

    RECRUITING

    Indianapolis, Indiana, 46256, United States

  • Florida Cancer Specialists

    RECRUITING

    Sarasota, Florida, 34232, United States

  • Hosp Univ Fund Jimenez Diaz

    RECRUITING

    Madrid, 28040, Spain

  • Hosp Univ Hm Sanchinarro

    RECRUITING

    Madrid, 28050, Spain

  • Hosp Univ Vall D Hebron

    RECRUITING

    Barcelona, 08035, Spain

  • Hosp. Univ. 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Severance Hospital Yonsei University Health System

    RECRUITING

    Seoul, 03722, South Korea

  • Start Midwest

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

  • Swedish Cancer Institute

    RECRUITING

    Seattle, Washington, 98104, United States

  • University of Colorado Denver Anschultz Medical Campus

    RECRUITING

    Aurora, Colorado, 80045, United States

Conditions

Explore the condition pages connected to this study.