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New combo aims to stall advanced stomach cancer

NCT ID NCT07070466

First seen Mar 15, 2026 · Last updated Jun 12, 2026 · Updated 17 times

Summary

This study tests a new drug called ivonescimab combined with standard chemotherapy (FOLFOX) in people with advanced HER2-negative stomach or esophagus cancer that has not been treated before. The goal is to see if the combination can keep the cancer from growing for at least 6 months. About 40 participants will receive the treatment, and researchers will monitor side effects and tumor response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA

    RECRUITING

    Santa Monica, California, 90404, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Esophageal Neoplasms gastric neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.