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Heart drug tested as migraine shield in small study

NCT ID NCT04853797

First seen Jan 09, 2026 · Last updated May 19, 2026 · Updated 23 times

Summary

This study tested whether ivabradine, a medicine that slows the heart rate, could prevent migraine attacks triggered by a substance called levcromakalim. Thirty-seven adults with migraine without aura took part. Researchers measured how many migraine attacks occurred after taking ivabradine compared to a placebo. The goal was to see if ivabradine could block the migraine-causing effects of levcromakalim.

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Contacts and locations

Locations

  • Danish Headache Center

    Glostrup Municipality, 2600, Denmark

  • Danish Headache Centre, Rigshospitalet-Glostrup

    Glostrup, Region Sjælland, 2600, Denmark

Conditions

Explore the condition pages connected to this study.