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Blood pressure cuff hack may shield aging hearts during workouts

NCT ID NCT07497659

Symptom relief Sponsor: Universidade Federal do Triangulo Mineiro Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether briefly cutting off blood flow to the legs (ischemic preconditioning) before resistance exercise could lower heart strain in women aged 60 and older. Thirty physically active older women did two exercise sessions—one with the real cuff procedure and one with a fake version. The goal was to see if the real procedure reduced cardiac workload after exercise, potentially making workouts safer for aging hearts.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ischemic preconditioning (brief blood flow restriction using a blood pressure cuff)
What this could lead to
If it works, this could point toward a simple, non-drug way to make resistance exercise safer for older women by reducing heart strain.
What could go wrong
This is a small, early-phase study with only 30 participants, so results may not apply broadly. The effect may be too small to matter in real-world exercise.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

May 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 70 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female participants aged 60 years or older * Physically independent * Engaged in regular physical activity (at least two sessions per week for the last three months) * Cleared for exercise participation by a cardiologist following clinical evaluation * Able to safely perform resistance exercise * Provided written informed consent Exclusion Criteria: * \- History of cardiovascular events such as myocardial infarction or stroke * Uncontrolled hypertension (≥160/105 mmHg) * Diabetes mellitus * Current smoking or alcohol abuse * Musculoskeletal limitations that impair exercise performance * Cognitive or communication impairments that interfere with understanding instructions

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Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood pressure Heart rate Hemodynamic response Rating of perceived exertion

Contacts and locations

Locations

  • Federal University of Triângulo Mineiro (UFTM)

    Uberaba, Minas Gerais, +55, Brazil

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