Can a 5-Minute clamp before surgery save lives?
NCT ID NCT03718312
First seen Jun 19, 2026 · Last updated Jun 19, 2026
Summary
This study tested whether briefly stopping blood flow to the aorta before surgery (called ischemic pre-conditioning) could reduce complications in people undergoing open repair of a thoracoabdominal aortic aneurysm. 65 patients were randomly assigned to receive either the pre-conditioning procedure or standard clamping. The main goals were to see if it lowered the chance of serious lung or kidney problems after surgery.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
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Locations
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University Hospital, Rouen
Rouen, 76031, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ischemic pre-conditioning (brief clamping and release of the aorta before surgery)
What this could lead to
If it works, this could reduce serious lung and kidney complications after major aortic surgery.
What could go wrong
This is a small, completed trial with only 65 participants, so results may not apply to everyone. The procedure itself carries risks during the clamping phase.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.