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Dry eye showdown: light therapy vs warm compress – but study never started

NCT ID NCT04920396

Symptom relief Sponsor: Aston University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study planned to compare intense regulated pulsed light (IRPL) therapy with daily warm compresses for people with dry eye caused by meibomian gland dysfunction. Researchers aimed to measure symptom scores and tear film stability. However, the trial was withdrawn before enrolling any participants, so no data were collected.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Intense regulated pulsed light (IRPL) therapy device
What this could lead to
If it worked, IRPL could offer a more effective option than warm compresses for relieving dry eye symptoms.
What could go wrong
The trial was withdrawn with no participants enrolled, so no results exist. IRPL may not prove better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Started

Jun 2021

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Willing and able to provide informed consent and participate in the required study visit * Subjects determined to have signs and symptoms of evaporative Dry Eye disease due to MGD, defined by the following: * OSDI score \>13 and * NITBUT \<= 10sec Exclusion Criteria: * No use of warm compresses, intense pulsed light therapy or other lid warming treatment in the past 6 Months * Patients with greater 75% meibomian gland loss * Presence of ocular pathology or systemic conditions other than previously diagnosed moderate or severe chronic dry eye and/or Sjogren's syndrome, that in the investigator's judgment may affect the testing for, or diagnosis of, dry eye if present * Use of prescribed ocular topical medication (e.g., anti-hypertensive, steroid, Cyclosporin A, antibiotic) within the last 24 hours * Artificial tear usage within 2 hours prior to study testing * Other invasive ocular diagnostic testing within 2 hours prior to study testing * Eye makeup present on the eye lid within 10 minutes prior to study testing

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Conditions

The condition(s) this trial relates to.

Meibomian Gland Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Meibomian gland dysfunction

Contacts and locations

Locations

  • Market Mall Eye Clinic - Calgary, AB

    Calgary, Alberta, AB T3A 0E2, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.