Can a nasal spray soothe dry eyes? new study investigates

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Is 18 years of age and has full legal capacity to volunteer (no max age requirement) * Baseline Ocular Surface Disease Index (OSDI) \>13 * Has mild to moderate MGD * Has best corrected visual acuity of 20/40 or better * Has had an oculo-visual examination in the last two years * Is willing to continue other daily dry eye management regimen (e.g., warm compresses, and/or eyelid margin cleaning) * Is willing to discontinue other prescription medications for dry eye disease (DED) management * Is willing to stop any topical eye drops before all planned visits * Has read, understood, and completed the informed consent letter Exclusion Criteria: * Is participating in any other type of clinical or research study * Is currently pregnant, nursing, lactating, or planning a pregnancy * Is currently having \>50% blockage of Meibomian glands in more than two eyelids or significant atrophy (i.e., severe MGD) * Is currently using any topical ocular medications * Has chronic or currently active sinus related problems * Has blepharitis \> grade 1 * Has active ocular infections * Has a condition or in a situation which, in the examiner's opinion, may put the subject at significant risk, may confound the study results, or may significantly interfere with their participation in the study * Has received Rx DED treatment within one week of enrollment * Has received any thermal or light-based DED treatment within 30 days of enrollment * Has significant corneal epithelial defects * Has abnormal eyelid anatomy * Has corneal neuropathic pain * Has chronic or recurrent epistaxis (nosebleeds), coagulation disorders, or other conditions that may have led to a clinically significant increased risk of bleeding * Has any intraocular surgery including trabeculectomy (MIGS, laser, or small incision glaucoma surgery allowed), extraocular surgery in either eye within 3 months, or refractive surgery within 12 months of enrollment * Has a known allergy to a product used in this study