New drug combo aims to boost chemoradiation for head and neck cancer
NCT ID NCT05172245
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 25 times
Summary
This early-phase study tests whether adding the experimental drug ipatasertib to standard chemotherapy and radiation is safe for people with advanced head and neck cancer. Ipatasertib may help stop cancer cells from growing. The study involves about 46 adults and aims to find the best dose with the fewest side effects.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Atrium Health Cabarrus/LCI-Concord
ACTIVE_NOT_RECRUITINGConcord, North Carolina, 28025, United States
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Carolinas Medical Center/Levine Cancer Institute
ACTIVE_NOT_RECRUITINGCharlotte, North Carolina, 28203, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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Montefiore Medical Center - Moses Campus
RECRUITINGThe Bronx, New York, 10467, United States
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Montefiore Medical Center-Einstein Campus
RECRUITINGThe Bronx, New York, 10461, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Rutgers Cancer Institute of New Jersey
RECRUITINGNew Brunswick, New Jersey, 08903, United States
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Rutgers New Jersey Medical School
RECRUITINGNewark, New Jersey, 07101, United States
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University Health Network-Princess Margaret Hospital
SUSPENDEDToronto, Ontario, M5G 2M9, Canada
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University of Cincinnati Cancer Center-UC Medical Center
RECRUITINGCincinnati, Ohio, 45219, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Cincinnati Cancer Center-West Chester
RECRUITINGWest Chester, Ohio, 45069, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Kansas Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Kansas Clinical Research Center
RECRUITINGFairway, Kansas, 66205, United States
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University of Kansas Hospital-Westwood Cancer Center
RECRUITINGWestwood, Kansas, 66205, United States
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University of Kentucky/Markey Cancer Center
RECRUITINGLexington, Kentucky, 40536, United States
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University of Maryland/Greenebaum Cancer Center
RECRUITINGBaltimore, Maryland, 21201, United States
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University of Virginia Cancer Center
SUSPENDEDCharlottesville, Virginia, 22908, United States
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VCU Massey Comprehensive Cancer Center
RECRUITINGRichmond, Virginia, 23298, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.