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New combo therapy aims to fight prostate cancer while preserving sexual function

NCT ID NCT04025372

First seen Jan 04, 2026 · Last updated May 24, 2026 · Updated 18 times

Summary

This study tests whether a newer hormone drug (darolutamide) combined with radiation works as well as standard hormone therapy for intermediate-risk prostate cancer, but with fewer side effects on erections. About 234 men will take part. The goal is to control the cancer while helping men maintain erectile function.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Associated Medical Professionals of NY

    Syracuse, New York, 13210, United States

  • Beth Israel Deaconness Medical Center

    Boston, Massachusetts, 02115, United States

  • Brigham and Women Hospital

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Medical Center

    Milford, Massachusetts, 01757, United States

  • Dana-Farber/Brigham and Women's Cancer Center in Clinical Affiliation with South Shore Hospital

    South Weymouth, Massachusetts, 02190, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • NYU Long Island

    Garden City, New York, 11530, United States

  • Stamford Hospital

    Stamford, Connecticut, 06904, United States

  • Washington University School of Medicine in St. Louis

    St Louis, Missouri, 63108, United States

  • XCancer Omaha / Urology Cancer Center

    Omaha, Nebraska, 68130, United States

Conditions

Explore the condition pages connected to this study.