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Could a single spray of anesthetic ease chest tube pain after lung surgery?

NCT ID NCT07294755

Symptom relief Sponsor: Chinese PLA General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether spraying a local anesthetic into the chest cavity after lung surgery can reduce pain from drainage tubes. 300 adults having keyhole lung surgery will be randomly assigned to receive either one of two anesthetic sprays or a placebo. Pain levels, sleep quality, and side effects will be tracked for three days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ropivacaine and tetracaine (local anesthetics)
What this could lead to
If it works, this could offer a simple, single-dose way to ease severe pain from chest tubes after lung surgery, reducing the need for stronger painkillers.
What could go wrong
This is an early-stage, single-center study. The effect may be small or short-lived, and there is a risk of side effects from the anesthetics, such as allergic reactions or nerve issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years old; * American Society of Anesthesiologists (ASA) physical status classification Ⅰ-Ⅲ, and patients undergoing pulmonary resection via video-assisted thoracic surgery (VATS) under general anesthesia; * Voluntarily signing the informed consent form;(4) Body Mass Index (BMI) ranging from 18 to 25 kg/m². Exclusion Criteria: * Patients with American Society of Anesthesiologists (ASA) physical status classification \>Ⅲ; * Patients allergic to amide-type local anesthetics; * Patients with recent intrathoracic infection; * Patients with a history of previous pulmonary surgery; * Patients with long-term alcohol abuse or chronic use of sedatives and analgesics; * Patients with severe hepatic or renal insufficiency; * Patients refusing to participate in the study; * Patients unable to complete the Numeric Rating Scale (NRS); * Patients expected to be admitted to the Intensive Care Unit (ICU) postoperatively; * Patients with a Mini-Mental State Examination (MMSE) score \<18; * Pregnant or lactating women; * Patients with a history of chronic pain; * Patients not requiring indwelling closed thoracic drainage tube postoperatively; * Patients converted from video-assisted thoracic surgery (VATS) to thoracotomy intraoperatively.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative analgesia

How to take part

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  1. The official record

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