Gut clues could unlock Sjogren's mystery
NCT ID NCT03841318
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether immune cells from the intestine play a role in Sjogren's syndrome, an autoimmune disease that causes dry eyes and mouth. Researchers examined saliva gland samples from 57 adults suspected of having Sjogren's. The goal was to better understand the disease and possibly find new treatment ideas.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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57 people
The number who actually took part.
- Started
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Aug 2020
- Finished
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Sep 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Suspicion of Sjogren's syndrome based on 2016 American College of Rheumatology (ACR) criteria; * Age ≥ 18 years * Being affiliated to health insurance * Willing to participate Exclusion Criteria: * Pregnant or breastfeeding women, * Patient concerned by articles L 1121-5 to L 1121-8 (persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU de Bordeaux - Service de médecine interne
Bordeaux, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Do rheumatic diseases quietly damage the Eye's oil glands?
- A swallowable spy pill could unlock Sjögren's secrets
- Experimental biologic CND319 takes first steps toward taming autoimmune diseases
- Study aims to sharpen Sjögren's diagnosis
- Are women with autoimmune diseases getting the gynecological care they need?