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Can intermittent fasting help after weight loss surgery?

NCT ID NCT06766747

Disease control Sponsor: Hospital Universitario San Ignacio Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested whether intermittent fasting (eating very little 2 days a week) works better than daily calorie restriction for people who regained weight after bariatric surgery. Sixteen adults who had surgery at least a year ago followed one of the two diets for 12 weeks. Researchers measured weight loss and body fat changes to see which approach was more effective.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Intermittent fasting (alternate-day, 75% calorie restriction 2 days per week) and continuous calorie restriction
What this could lead to
If it works, this could offer a practical dietary option for people who regain weight after bariatric surgery, without needing to count calories every day.
What could go wrong
This is a very small study (16 people) with no blinding, so results may not apply widely. The weight loss phase is only 12 weeks, so long-term effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

16 people

The number who actually took part.

Started

Dec 2023

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 69 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Patients between 18 and 69 years of age treated with primary and/or secondary bariatric surgery with more than 1 year of postoperative. 2.3.3 INCLUSION CRITERIA * 10% weight gain with respect to the minimum postoperative weight and/or * Weight gain rate ≥0.50% with respect to previous weight. * Supplementation with ferrous sulfate, cyanocobalamin and cholecalciferol, according to clinical criteria. * Not having modified the therapy in the last 3 months * Access to mobile phone with data. * Agree to participate in the study including signing informed consent. 2.3.4 EXCLUSION CRITERIA. * Patient diagnosed with type 1 diabetes mellitus. * Patient diagnosed with type 2 diabetes mellitus treated with insulin. * History of an eating disorder such as anorexia or bulimia. • Untreated vitamin B12, iron, calcium, and/or vitamin D deficiency. * History of hospitalization for cardiovascular disease (angina, myocardial infarction, or stroke) 3 months prior to the study. * Use of antidepressant or anti-anxiety medications * Use of medications that affect the results of the study (weight loss medications) * Unable to keep a food diary or activity log for 7 consecutive days during screening * Cognitive impairment that, in the opinion of the principal investigator or study physician, would result in failure to cooperate with study procedures. * Active neoplastic disease. * Pregnancy or breast-feeding, or planning to become pregnant during the study period * Significant psychiatric illness, kidney disease, severe liver disease, or other illness that affects the ability to complete the study.

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Conditions

The condition(s) this trial relates to.

Intermittent Fasting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bariatric surgery complications Intermittent fasting Obesity prevention

Contacts and locations

Locations

  • Hospital Universitario San Ignacio.

    Bogotá, Bogota D.C., 111021, Colombia

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